Upcoming Events
Dow AgroSciences News
EXZACT in the News
EXZACT Publications 


2012 Events: EXZACT™ Presentations

May 5, 2012
EMBO Workshop:
Genetic Stability & Change: Genome maintenance mechanisms in plants


June 2012
SIVB Meeting
Seattle, WA

June 19, 2012
BIO International Convention
Boston, MA

August 2012
Plant Biotechnology USA
Raleigh, NC

Dow AgroSciences in the News:

May 2, 2011
Dow AgroSciences, Oregon State University Enter into Research Agreement for Tree Research Using EXZACT™ Precision Technology
Project Aims to Accelerate Tree Biotechnology

Read the full press release

September 20, 2010
Dow AgroSciences, Wageningen UR Enter into Agreement to Use EXZACT™ Precision Technology
Research will focus on improving potato through precise genome modification

Read the full press release

September 09, 2010
Dow AgroSciences, KWS Enter Into Agreement for Research & Product Development
Companies to Use EXZACT™ Precision Technology for Sugar Beet Improvement

Read the full press release

April 16, 2010
Dow AgroSciences, Iowa State University Enter into Research Agreement Using EXZACT™ Precision Technology in Algae
Project Aims to Enhance Development of Renewable Bioproducts

Read the full press release

EXZACT in the News:

Gruskin, D. Agbiotech 2.0 Nature Biotechnology 30, 211-214 (2012) | doi: 10.1038/nbt.2144
Published online 07 March 2012
As parts of the developing world embrace biotech, the focus is shifting from food production to fuels, industrial chemicals and even drugs. Daniel Grushkin investigates.
Abstract | Nature Subscribers Full Text | PDF (330 KB) - Agbiotech 2.0   

Waltz, E. Tiptoeing around transgenics Nature Biotechnology 30, 215-217 (2012) |  doi:10.1038/nbt.2143
Published online 07 March 2012
New techniques for manipulating plant genomes are yielding plants touted as nontransgenic. Will that relieve regulatory burden?  Emily Waltz investigates.
Abstract | Nature Subscribers Full Text | PDF (170 KB) - Tiptoeing around transgenics

Lusser, M., Parisi, C., Plan, D., Rodriguez-Cerezo, E. Deployment of new biotechnologies in plant breeding Nature Biotechnology 30, 231-239 (2012) | doi:10.1038/nbt.2142
Published online 07 March 2012
The first crops obtained through new plant breeding techniques are close to commercialization. Regulatory issues will determine the adoption of the techniques by breeders.
Abstract | Nature Subscribers Full TextPDF (666 KB) - Deployment of new biotechnologies in plant breeding | Supplementary information 

EXZACT Publications

Gupta, M., et al., Transcriptional activation of Brassica napus -ketoacyl-ACP synthase II with an engineered zinc finger protein transcription factor. Plant Biotechnology Journal, 2012: p. 1-9. 
Using designed zinc-finger proteins (ZFP) fused to transcriptional activators, two native canola genes were up-regulated resulting in a statistically significant decrease in saturated fatty acid content.  The results demonstrate how ZFP fused to transcriptional factors can be used to regulate the expression of native plant genes to elicit specific phenotypic modifications of agronomic important traits. View the full article on PBJ online.

Strange T.L., Petolino J.F., Targeting DNA to a previously integrated transgenic locus using zinc finger nucleases. Methods Mol Biol, 2012. 847: p 391-7

Petolino, J.F., et al., Zinc finger nuclease-mediated transgene deletion. Plant Mol Biol, 2010. 73(6): p. 617-28

Cai, C.Q., et al., Targeted transgene integration in plant cells using designed zinc finger nucleases. Plant Mol Biol, 2009. 69(6): p. 699-709

Shukla, V.K., et al., Precise genome modification in the crop species Zea mays using zinc-finger nucleases. Nature, 2009. 459(7245): p. 437-U156.