Overview of EXZACT™ Precision Technology 
EXZACT™ Precision Technology is an exciting breakthrough in genetic modification for plants, whether they be crops, vegetables, ornamentals, or any other variety used for agriculture or research.
What is EXZACT™ Precision Technology? 
EXZACT™ Precision Technology is a novel and versatile toolkit that allows plant biotechnologists to engineer precise genome modifications in plants. It allows scientists and developers to add, edit, and delete genes from plant genomes efficiently. For the first time, genome modification is practical and feasible – and applicable across many different types of plant species.
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How does EXZACT™ Precision Technology work? 
EXZACT™ Precision Technology is based on proprietary zinc-finger protein designs. With zinc-finger proteins, the double-stranded DNA is cut, allowing the plant to use its natural repair mechanisms. These mechanisms can add, edit, or even delete specifically-targeted genes within the plant genome.
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Is EXZACT™ Precision Technology proven? 
EXZACT™ Precision Technology has been tested in a diverse variety of crop and plant species. For example, research published in the journal Nature focused on corn, showing that not only can genetic traits be inserted into specifically-targeted, predetermined sites in the plant genome, but those traits can be passed on to several generations of corn – stably and reliably.
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Why is EXZACT™ Precision Technology different from current plant genome modification methods? 
Traditional genome modification relies on methods that make changes in DNA at random sequences, or locations. EXZACT™ Precision Technology, by contrast, uses zinc-finger proteins to target specific locations in the DNA sequence, so scientists and developers can predetermine which gene they want to add, delete, or modify – thereby producing predictable, reliable, stable results.
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How is EXZACT™ Precision Technology likely to be used? 
EXZACT™ Precision Technology can be used to simplify and accelerate trait stacking in plants and crops, as well as to develop new traits and discover new genes.
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What are the benefits of EXZACT™ Precision Technology? 
EXZACT™ Precision Technology benefits both agriculture and basic plant science. For instance, one of the benefits to agriculture is the potential for accelerated development of plants with novel or combination (stacked) traits, which is what the marketplace demands.
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How does Dow AgroSciences plan to use EXZACT™ Precision Technology? 
EXZACT™ Precision Technology is an integral part of Dow AgroSciences’ ongoing trait development and research pipeline. We are also working with partners and licensees to explore new opportunities and make EXZACT™ Precision Technology the “gold standard” for genome modification in crops and other plants.
Visit News and Events to read press releases about partnerships and licensees.
Still have questions? Be sure to visit What is EXZACT™? for a more complete description of this breakthrough technology and The Science of EXZACT™ for a deeper dive into its research and application. Or contact us to learn how you might become a research partner or licensee.
